What Receptors & Enzymes Does CBD Interact With?

For those of you interested in the finer biochemical interactions of cannabis — you’re not alone.

Here’s a list of the receptors and enzymes CBD has been shown to interact with:

• 15‐lipoxygenase
• 5HT1A receptor agonist (serotonin receptor)
• 5‐lipoxygenase
• Adenosine (A2a)
• Arylalkylamine N‐acetyltransferase
• FAAH
• Glutathione peroxidase
• Glutathione reductase
• Indoleamine‐2,3‐dioxygenase
• Mg2+‐ATPase
• Phospholipase A2
• PPARγ nuclear receptor
• Vanilloid pain receptors (TRPV1, TRPV2, TRPV3)

Interestingly, CBD affects the psychedelic receptors — which are the same receptors used by magic mushrooms or LSD for causing their hallucinogenic effects. CBD interacts with this receptor differently — which is why it lacks the same psychedelic qualities.